Myristoyl coenzyme A Sodium Salt (CAS 3130-72-1) - 10mg

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    Alternate Names: Myristoyl coenzyme A Sodium Salt is also known as Tetradecanoyl Coenzyme A Sodium Salt.


    Application: Myristoyl coenzyme A is a derivative of Coenzyme A that contains myristic acid, a long-chain fatty acid.


    CAS Number: 3130-72-1


    Purity: ≥94%


    Molecular Weight: 977.90


    Molecular Formula: C35H62N7O17P3S•xNa


    Myristoyl coenzyme A is a derivative of Coenzyme A, also known as CoA. Myristoyl coenzyme A. contains the long-chain fatty acid myristic acid. During myristoylation, it acts as a substrate for N-myristoyltransferase. Myristoyl coenzyme A is also a substrate in the de novo synthesis of phosphatidylinositol. Myristoyl coenzyme A is also known as Myristoyl-CoA, Tetradecanoyl-CoA, Myristoyl Coenzyme A free acid, Tetradecanoyl Coenzyme A, and S-tetradecanoate, coenzyme A, monohydrate.



    References:

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    2. Aspergillus nidulans swoF encodes an N-myristoyl transferase.  |  Shaw, BD., et al. 2002. Eukaryot Cell. 1: 241-8. PMID: 12455958
    3. Myristoyl-CoA:protein N-myristoyltransferases: isoform identification and gene expression in retina.  |  Rundle, DR., et al. 2004. Mol Vis. 10: 177-85. PMID: 15041955
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    5. A peroxisomal acyltransferase in mouse identifies a novel pathway for taurine conjugation of fatty acids.  |  Reilly, SJ., et al. 2007. FASEB J. 21: 99-107. PMID: 17116739
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    9. A fluorescence-based assay for N-myristoyltransferase activity.  |  Goncalves, V., et al. 2012. Anal Biochem. 421: 342-4. PMID: 22051857
    10. A highly convergent synthesis of myristoyl-carba(dethia)-coenzyme A.  |  Tautz, L. and Rétey, J. 2010. European J Org Chem. 2010: 1728-1735. PMID: 22347809
    11. Myristate-derived d16:0 sphingolipids constitute a cardiac sphingolipid pool with distinct synthetic routes and functional properties.  |  Russo, SB., et al. 2013. J Biol Chem. 288: 13397-409. PMID: 23530041
    12. Histone Deacetylase 11 Is a Fatty-Acid Deacylase.  |  Kutil, Z., et al. 2018. ACS Chem Biol. 13: 685-693. PMID: 29336543
    13. Mapping the myristoylome through a complete understanding of protein myristoylation biochemistry.  |  Giglione, C. and Meinnel, T. 2022. Prog Lipid Res. 85: 101139. PMID: 34793862
    14. N-Myristoyltransferase, a Potential Antifungal Candidate Drug-Target for Aspergillus flavus.  |  Wang, Y., et al. 2023. Microbiol Spectr. 11: e0421222. PMID: 36541770