Histone H3K9ac (Acetyl H3K9) Polyclonal Antibody - 100ul
Background
Histone H3- along with H2A, H2B and H4- is involved in the structure of chromatin in eukaryotic cells. Histone H3 can undergo several different types of epigenetic modifications that influence cellular processes. These modifications, including acetylation, phosphorylation, methylation, ubiquitination, and ADP-ribosylation occur on the N-terminal tail domains of histone H3, which results in remodeling of the nucleosome structure into an open conformation more accessible to transcription complexes. In most species, histone H3 is primarily acetylated at lysine 9, 14, 18, and 23.
Description
Histone H3K9ac (Acetyl H3K9) Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Formulation:
PBS with 0.01% thiomersal, 50% glycerol, pH7.3
Specificity
Broad Range, Human, Mouse, Rat
Isotype
IgG
Purification
Affinity Purified
Immunogen
A synthetic acetylated peptide around K9 of human Histone H3 (NP_003520.1).
Storage
Shipped at 4°C. Store at -20°C. Avoid multiple freeze/thaw cycles.
Alternative Names
H3K9ac antibody, H3K9a antibody
Application
WB, IHC, IF, IP, ChIP, ChIPseq; Recommended dilution: WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:200, IP 1:50 - 1:200, ChIP 1:20 - 1:100, CHIPseq 1:20 - 1:50