Synonyms: Tumor necrosis factor receptor superfamily member 25, Apo-3, Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor DR3, Apoptosis-mediating receptor TRAMP, Death receptor 3
Species: Human
Concentration: 1.0 mg/ml, lot specific
Description: TNFRSF25 is the receptor for TNFSF12/APO3L/TWEAK. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins.
Entrez Symbol: TNFRSF25
Uniprot Name: Tumor necrosis factor receptor superfamily member 25
Uniprot ID: Q93038
Purity: > 95% as determined by SDS-PAGE
Specificity: Human TNFRSF25
Isotype: IgG2-lambda
Clone: PTX25
Formulation: 0.01M PBS buffer, pH 7.4
Purification: Protein A/G affinity chromatography
Application: FC
Storage/Stability: Store at -20°C to -80°C for up to 1 year